Sunday, 8 April 2012

Too much sitting linked to shortened lives


REUTERS - People who spent a lot of time sitting at a desk or in front of a television were more likely to die than those who were only sedentary a few hours a day, according to an Australian study that looked at death rates during a three-year period.
Researchers, whose results appeared in the Archives of Internal Medicine, found that the link between too much time sitting and shortened lives stuck even when they accounted for how much moderate or vigorous exercise people got, as well as their weight and other measures of health.
That suggests that shifting some time from sitting to light physical activity, such as slow walking or active chores, might have important long-term benefits, they added.
"When we give people messages about how much physical activity they should be doing, we also need to talk to them about reducing the amount of hours they spend sitting each day," said Hidde van der Ploeg, the new study's lead author from the University of Sydney.
Of more than 200,000 adults age 45 and older, van der Ploeg and her colleagues found that people who reported sitting for at least 11 hours a day were 40 percent more likely to die during the study than those who sat less than four hours daily.
That doesn't, however, prove that sitting itself cuts people's lives short, she noted, adding that there could be other unmeasured differences between people who spend a lot or a little time sitting each day.
The team surveyed about 220,000 people from New South Wales, Australia, between 2006 and 2008, including questions about participants' general health and any medical conditions they had, whether they smoked and how much time they spent both exercising and sitting each day.
Then the research team tracked responders using Australian mortality records for an average of almost three years, during which 5,400 - between two and three percent - died.
They found that the extra risk tied to sitting held up regardless of whether people were normal weight or overweight, how much time they spent working out and whether they were healthy or had pre-existing medical conditions.
Van der Ploeg said too much sitting may affect blood vessels and metabolism by increasing fats in the blood and lowering "good" cholesterol levels.
"When you are standing or walking, your leg muscles are constantly working which helps to clear blood glucose and blood fats from the blood stream," she said. "If you are sitting, this is not happening because the muscles are not active."
The findings are consistent with other recent studies suggesting health consequences from too much sitting, said Mark Tremblay, an obesity and activity researcher at Children's Hospital of Eastern Ontario in Canada.
"Sitting or reclining, especially in front of screens, is bad for you regardless of your age," said Tremblay, who wasn't involved in the study.
He added that even though people tend to think they're okay as long as they work out a certain amount a day, that's not necessarily the case.
"Getting your 30 minutes of physical activity five times a week is not insurance against chronic disease.
Both he and Van der Ploeg said there were ways that even people who have jobs involving a lot of desk work can train themselves to regularly interrupt sedentary behavior, such as standing up while on the phone or holding a stand-up meeting.
"Make sure the fax machine is four steps away from you, not within reaching distance," Tremblay said.
"Drink enough water that you have to pee four times a day. Stand up, stretch, walk around a little bit, say 'hi' to your friend in the cubicle next door."
SOURCE: http://bit.ly/Hi0niK
(Reporting from New York by Genevra Pittman at Reuters Health; editing by Elaine Lies)
Source: Yahoo!

Cure for baldness closer to reality


Washington, Mar 22 (ANI): Researchers have discovered an abnormal amount of a protein called Prostaglandin D2 in the bald scalp of men with male pattern baldness.

The discovery by researchers at Perelman School of Medicine at the University of Pennsylvania may lead directly to new treatments for the most common cause of hair loss in men.

In both human and animal models, researchers found that a prostaglandin known as PGD2 and its derivative, 15-dPGJ2, inhibit hair growth.

The PGD2-related inhibition occurred through a receptor called GPR44, which is a promising therapeutic target for androgenetic alopecia in both men and women with hair loss and thinning.

Male pattern baldness strikes 8 of 10 men under 70 years old, and causes hair follicles to shrink and produce microscopic hairs, which grow for a shorter duration of time than normal follicles.

Researchers took an unbiased approach when scanning for potential biological causes of baldness, looking in scalp tissue from balding and non-bald spots from men with male pattern baldness and then corroborating findings in mouse models.

They found that levels of PGD2 were elevated in bald scalp tissue at levels 3 times greater than what was found in comparative haired scalp of men with androgenetic alopecia.

When PGD2 was added to cultured hair follicles, PGD2-treated hair was significantly shortly, while PGD2's derivative, 15-dPGJ2, completely inhibited hair growth.

"Although a different prostaglandin was known to increase hair growth, our findings were unexpected, as prostaglandins haven't been thought about in relation to hair loss, yet it made sense that there was an inhibitor of hair growth, based on our earlier work looking at hair follicle stem cells," said George Cotsarelis, MD, chair and professor of Dermatology, and senior author on the studies.

In a Penn study published last year, underlying hair follicle stem cells were found intact, suggesting that the scalp was lacking an activator or something was inhibiting hair follicle growth.

Prostaglandins are well characterized for their role in many bodily functions - controlling cell growth, constricting and dilating smooth muscle tissue - and a different prostaglandin (F2alpha) is known to increase hair growth.

Researchers found that as PGD2 inhibits hair growth, other prostaglandins work in opposition, enhancing and regulating the speed of hair growth.

While these studies looked at AGA in men, the researchers noted that prostaglandins may represent a common pathway shared by both men and women with AGA.

Future studies, potentially testing topical treatments that may target GPR44, can determine whether targeting prostaglandins will benefit woman with AGA as well.

The study has been published in Science Translational Medicine. (ANI)

Source: Yahoo!

Natural wonders – Green tea


Enough and beyond has been written about green tea and its numerous health benefits. How exactly does it help your body? Read on to find out.

Green tea and its nutrients

All kinds of tea, be it black, green or oolong, comes from the Camellia sinensis plant. The colour of the tea depends upon the amount of fermentation it has been through. Oolong tea is partially fermented, black tea is completely fermented and green tea is not fermented at all. It is produced by steaming fresh tea leaves at very high temperature.
That tea is rich in antioxidants is a given, but green tea is known to contain large amounts of polyphenols, thearubigins, epicatechins and catechins – all types of an antioxidant known as flavanoids.

Green tea and its health benefits

Heart healthy: Regular consumption of green tea has been known to reduce overall cholesterol levels, especially the bad LDL cholesterol which ultimately reduces the risk of heart attacks and heart diseases.
Watch our interview with Dr. Devi Shetty to know more about staying heart healthy.

Fights cancer: Catechins present in green tea, are the flavanoids which fight free radicals that damage DNA and increase the risk of cancer. Since green tea is not put through a whole lot of processing, catechins, especially epigallocatechin-3-gallate (EGCG) are available in larger numbers.

Helps you lose weight: Can a simple activity like drinking green tea help you lose weight? Recent studies show that catechins help combat accumulated fat and aid in weight loss. Experts say that this fat reducing property catechins can help in a number of lifestyle disease, including obesity.

Also read: Top 10 best diet tips
Boosts your immune system: The antioxidants in green tea help give your immune system a boost of good health which helps keep common ailments like the flu away.
Happy teeth: Catechins are also antibacterial, which is why they are so great in fighting tooth decay, gum diseases and bad breath. Additionally, they also reduce the formation of plaque.
Also read: Foods for healthy teeth
Prevents diabetes: Preliminary studies show that green tea may help to prevent or at the very least, slow down the onset of diabetes. The same study also suggested that green tea acts a very good agent in lowering your blood sugar.
Also read: Foods which help you control your diabetes
Improves bone health: Studies show that not only can drinking green tea help improve bone density and help reduce the risk of a fracture, it also encourages bone formation.
Reduces the risk of Parkinson’s and Alzheimer’s: Research shows that polyphenols  present in green tea helps in improving concentration, prevents memory loss and helps reduce the accumulation of brain damaging proteins in your body.
 Great for your skin: Not just as a drink, skin care products with green tea extracts are also wonderful for your skin as it helps your skin stay supple. The antioxidants in green tea are also known to help keep wrinkles at bay.
Experts suggest anywhere from 2-5 cups daily can help you rake in maximum benefit from this natural wonder. Try the decaffeinated version if you’re worried about the caffeine.
So are you ready to ditch your coffee for this healthy cuppa?

Source: Yahoo!

Save water: Simple ideas to cut water wastage at home


On World Water Day, mDhil puts together some efficient ways of cutting down water usage. Adopt what suits you best, and play your part in conserving water.
Save water: Simple ideas to conserve waterSave water: Simple ideas to conserve water
Check for leaking taps around the house.
Conservation of water is an essential practice today, whether or not you’re having water troubles at the moment. Simple changes can help save gallons of water a day. So make these changes and help conserve water.
  1. Washing veggies and fruits: Soak fruits and vegetables in a pot of water instead of putting them under running water to wash them.
  2. Water plants with water used to wash them: When you’re done with soaking your fruits and veggies, don’t throw the water down the drain, instead use it to water indoor plants.
  3. Don’t leave the tap open while brushing your teeth: Well, you’ve heard this one many times before. While brushing your teeth, wet the brush and turn off the tap. If you keep the tap running, you’re bound to waste litres of water in a week. Try and get your family to practice this too.
  4. Conserve water while washing dishes: When you wash your dishes put a stopper to the sink drain and fill it with water. When all the dishes have been scrubbed, rinse them of in that water.
  5. Get your toilet fixed: If you’re toilet is running, get it fixed. It’s most likely a part of the flapper that’s causing the leak, adjust it; if that doesn’t work, get a plumber.
  6. Get any other leakage fixed, too:The same applies to any leaking tap around the house… Make sure you get them fixed. All they might need is a new washer, and that isn’t too expensive. Also, look for any leaking pipes around the house.
  7. Soak pans before washing them: Soak pots and pans in water after use. This will save water while you’re trying to scrub off later on.
  8. Shorten your shower: Try and reduce your showering time. One way to cut down on your water usage, is to turn of the shower while soaping your body and shampooing your hair. Ask your family to adopt this practice, too. Better still, install water-saving shower-heads. They’ll save you loads of water.
  9. Defrost in the microwave: You don’t need to use running water to defrost frozen food. Instead stick it in the microwave for defrosting, or remove your frozen food and leave it out in advance.
  10. Use your washing machine only for full loads: If you use a washing machine, only wash full loads of laundry at a time. Also, if you’re shopping for a washing machine, experts are of the opinion that top-loading machines use more water than front-loading ones. So you might be better off buying the latter.
  11. Don’t use the toilet as an ashtray or wastebasket: Every time you flush a cigarette butt, tissue or any other piece of trash, you waster tonnes of water.
  12. Rinse your razor in a mug: To rinse off your razor, either fill the sink with a few inches of warm water or a mug. This will rinse your razor just as well as running water, with far less waste of water.
  13. Instead of running water, use a broom to clean your driveways and corridors. You can wash them with water every once in while though.
  14. Don’t run the hose to wash your car: To clean your car or bike, use a bucket of soapy water. After that’s done, dip a sponge in clean water and wipe off soap. This way you’ll save litres of water.
Photograph via sxc.hu


Source: Yahoo!